(5R)-5-hydroxytriptolide inhibits the inflammatory cascade reaction in astrocytes

(5R)-5-hydroxytriptolide inhibits the inflammatory cascade reaction in astrocytes

Many studies have shown that (5R)-5-hydroxytriptolide is the optimal modified analogue of triptolide, possessing comparable immunosuppressive activity but much lower cytotoxicity than triptolide. Whether (5R)-5-hydroxytriptolide has preventive effects on neuroinflammation is unclear. This study was...

Full description

Bibliographic Details
Main Authors: Yan-Qiu Cui, Yan Zheng, Gui-Lian Tan, Dong-Mei Zhang, Jun-Ya Wang, Xiao-Min Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
neuroinflammation; (5R)-5-hydroxytriptolide; tumor necrosis factor-α; interleukin-1β; nitric oxide; nuclear factor-κB/P65; IκB-α; microglia; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=5;spage=913;epage=920;aulast=Cui

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=5;spage=913;epage=920;aulast=Cui

Similar Items