Patterns of surveillance for late effects of BCR-ABL tyrosine kinase inhibitors in survivors of pediatric Philadelphia chromosome positive leukemias

Patterns of surveillance for late effects of BCR-ABL tyrosine kinase inhibitors in survivors of pediatric Philadelphia chromosome positive leukemias

Abstract Background Targeted anticancer therapies such as BCR-ABL tyrosine kinase inhibitors (TKIs) have improved outcomes for chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL). However, little is known about long-term risks of TKIs in childr...

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Bibliographic Details
Main Authors: Stephanie M. Smith, Himalee S. Sabnis, Rebecca Williamson Lewis, Karen E. Effinger, John Bergsagel, Briana Patterson, Ann Mertens, Kathleen M. Sakamoto, Lidia Schapira, Sharon M. Castellino
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Tyrosine kinase inhibitors
Bcr-abl leukemia
Late-effects
Surveillance
CML
Ph + ALL
Online Access:https://doi.org/10.1186/s12885-021-08182-z

Internet

https://doi.org/10.1186/s12885-021-08182-z

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