Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells

Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.

Bibliographic Details
Main Authors: Hiroki Ikeda, Masamitsu Sone, Shinya Yamanaka, Takuya Yamamoto
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01679-x