N6-Methyladenosine METTL3 Modulates the Proliferation and Apoptosis of Lens Epithelial Cells in Diabetic Cataract

N6-Methyladenosine METTL3 Modulates the Proliferation and Apoptosis of Lens Epithelial Cells in Diabetic Cataract

N6-methyladenosine (m6A) is the most prevalent eukaryotic messenger RNA modification. Diabetic cataract (DC) is caused by high glucose (HG) in diabetes mellitus. However, the regulatory mechanism of m6A in the DC pathogenesis is poorly understood. In present research, we performed the m6A-RNA immuno...

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Bibliographic Details
Main Authors: Jun Yang, Jingshu Liu, Shaozhen Zhao, Fang Tian
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
N6-methyladenosine
human lens epithelial cells
diabetic cataract
METTL3
ICAM-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300743

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http://www.sciencedirect.com/science/article/pii/S2162253120300743

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