Structure, dynamics and implied gating mechanism of a human cyclic nucleotide-gated channel.

Cyclic nucleotide-gated (CNG) ion channels are nonselective cation channels, essential for visual and olfactory sensory transduction. Although the channels include voltage-sensor domains (VSDs), their conductance is thought to be independent of the membrane potential, and their gating regulated by c...

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Bibliographic Details
Main Authors: Yana Gofman, Charlotta Schärfe, Debora S Marks, Turkan Haliloglu, Nir Ben-Tal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1003976