Structure, dynamics and implied gating mechanism of a human cyclic nucleotide-gated channel.
Cyclic nucleotide-gated (CNG) ion channels are nonselective cation channels, essential for visual and olfactory sensory transduction. Although the channels include voltage-sensor domains (VSDs), their conductance is thought to be independent of the membrane potential, and their gating regulated by c...
Main Authors: | Yana Gofman, Charlotta Schärfe, Debora S Marks, Turkan Haliloglu, Nir Ben-Tal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-12-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1003976 |
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