Allele-specific regulation of matrix metalloproteinase-3 gene by transcription factor NFkappaB.

Allele-specific regulation of matrix metalloproteinase-3 gene by transcription factor NFkappaB.

Matrix metalloproteinase-3 (MMP3) is implicated in the pathogenesis and progression of atherosclerotic lesions. Previous studies suggested that MMP3 expression is influenced by a polymorphism (known as the 5A/6A polymorphism) in the promoter of the MMP3 gene and that this polymorphism is located wit...

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Bibliographic Details
Main Authors: Veronika Souslova, Paul A Townsend, Jelena Mann, Chris M van der Loos, Anna Motterle, Fulvio D'Acquisto, Derek A Mann, Shu Ye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2845631?pdf=render

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http://europepmc.org/articles/PMC2845631?pdf=render

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