Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

Hepatocellular cancers (HCC) are highly resistant to chemotherapy. TGFβ has been associated with chemoresistance in some human cancers but the mechanisms involved are unknown. We explored how TGFβ might contribute to altered responses to therapy by assessing the involvement and mechanistic contribut...

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Bibliographic Details
Main Authors: Kenji Takahashi, Irene K. Yan, Takayuki Kogure, Hiroaki Haga, Tushar Patel
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546314000436