Coordinated Acetylcholine Release in Prefrontal Cortex and Hippocampus Is Associated with Arousal and Reward on Distinct Timescales

Cholinergic neurotransmission throughout the neocortex and hippocampus regulates arousal, learning, and attention. However, owing to the poorly characterized timing and location of acetylcholine release, its detailed behavioral functions remain unclear. Using electrochemical biosensors chronically i...

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Bibliographic Details
Main Authors: Leonor M. Teles-Grilo Ruivo, Keeley L. Baker, Michael W. Conway, Peter J. Kinsley, Gary Gilmour, Keith G. Phillips, John T.R. Isaac, John P. Lowry, Jack R. Mellor
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716318071