Sox11 regulates mammary tumour-initiating and metastatic capacity in Brca1-deficient mouse mammary tumour cells

Little is known about the role of Sox11 in the regulation of mammary progenitor cells. Sox11 is expressed by mammary bud epithelial cells during embryonic mammary gland development and is not detected in mammary epithelial cells after birth. As Sox11 is an oncofetal gene, we investigated the effects...

Full description

Bibliographic Details
Main Authors: Siu Man Tsang, Hyojin Kim, Erik Oliemuller, Richard Newman, Naa-Anyima Boateng, Naomi Guppy, Beatrice A. Howard
Format: Article
Language:English
Published: The Company of Biologists 2021-05-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/14/5/dmm046037