IL-22-expressing murine lymphocytes: Plasticity and pathogenicity

IL-22 has multiple activities ranging from tissue repair to inflammation. To characterize the pathogenicity and plasticity of cells that produce IL-22 a novel reporter mouse strain was generated. Homeostatic IL-22 reporter expression was observed in intestinal lymphoid cells identified as CD4 T cell...

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Bibliographic Details
Main Author: Scott Kenneth Durum
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00662/full