Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function

Vascular endothelial growth factors (VEGFs) are key mediators of endothelial cell (EC) function in angiogenesis. Emerging knowledge also supports the involvement of axon guidance-related factors in the regulation of angiogenesis and vascular patterning. In the current study, we demonstrate that fibr...

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Bibliographic Details
Main Authors: Suvi Jauhiainen, Johanna P. Laakkonen, Kirsi Ketola, Pyry I. Toivanen, Tiina Nieminen, Takeshi Ninchoji, Anna-Liisa Levonen, Minna U. Kaikkonen, Seppo Ylä-Herttuala
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
angiogenesis
axon guidance factor
cell survival
endothelial cell
fibronectin-leucine-rich transmembrane protein
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00224/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00224/full

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