Integrative Analyses of miRNA-mRNA Interactions Reveal let-7b, miR-128 and MAPK Pathway Involvement in Muscle Mass Loss in Sex-Linked Dwarf Chickens

Integrative Analyses of miRNA-mRNA Interactions Reveal let-7b, miR-128 and MAPK Pathway Involvement in Muscle Mass Loss in Sex-Linked Dwarf Chickens

The sex-linked dwarf (SLD) chicken is an ideal model system for understanding growth hormone (GH)-action and growth hormone receptor (GHR) function because of its recessive mutation in the GHR gene. Skeletal muscle mass is reduced in the SLD chicken with a smaller muscle fiber diameter. Our previous...

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Bibliographic Details
Main Authors: Wen Luo, Shumao Lin, Guihuan Li, Qinghua Nie, Xiquan Zhang
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:International Journal of Molecular Sciences
Subjects:
sex-link dwarf chicken
growth hormone receptor
network
microRNA
muscle development
Online Access:http://www.mdpi.com/1422-0067/17/3/276

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http://www.mdpi.com/1422-0067/17/3/276

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