Functional and Expression Analyses of the Pneumocystis MAT Genes Suggest Obligate Sexuality through Primary Homothallism within Host Lungs

Fungi of the genus Pneumocystis are obligate parasites that colonize mammals’ lungs and are host species specific. Pneumocystis jirovecii and Pneumocystis carinii infect, respectively, humans and rats. They can turn into opportunistic pathogens in immunosuppressed hosts, causing severe pneumonia. Th...

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Bibliographic Details
Main Authors: S. Richard, J. M. G. C. F. Almeida, O. H. Cissé, A. Luraschi, O. Nielsen, M. Pagni, P. M. Hauser, Louis M. Weiss
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02201-17