Assessing the significance of conserved genomic aberrations using high resolution genomic microarrays.

Genomic aberrations recurrent in a particular cancer type can be important prognostic markers for tumor progression. Typically in early tumorigenesis, cells incur a breakdown of the DNA replication machinery that results in an accumulation of genomic aberrations in the form of duplications, deletion...

Full description

Bibliographic Details
Main Authors: Mitchell Guttman, Carolyn Mies, Katarzyna Dudycz-Sulicz, Sharon J Diskin, Don A Baldwin, Christian J Stoeckert, Gregory R Grant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1950957?pdf=render