Ambient PM particles reach mouse brain, generate ultrastructural hallmarks of neuroinflammation, and stimulate amyloid deposition, tangles, and plaque formation

Mice were exposed to ambient PM particles 8 h per day, 6 days per week, for twenty-four weeks in enrichment chambers, with real-time mass concentration of PM2.5 around 70 µg/m3, and the number of PM0.1 about 10,000-20,000/m3. The component analysis of PM particles by inductive coupled plasma emissio...

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Bibliographic Details
Main Authors: Saira Hameed, PhD, Jinzhuo Zhao, PhD, Richard N. Zare, PhD
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Talanta Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666831920300138