Zinc supplementation improves heme biosynthesis in rats exposed to lead

Background Lead acetate (Pb) inhibits heme biosynthesis through inhibition of d-aminolevulinic acid dehydrogenase (d-ALAD), copro porphyrinogen oxidase, and ferro chelatase. Zinc supplementation increases lead-binding metallothionein proteins. The purpose of this study was to find evidence that zin...

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Bibliographic Details
Main Authors: Budi Santosa, Hertanto Wahyu Subagio, Lisyani Suromo, Henna Rya Sunoko
Format: Article
Language:English
Published: Faculty of Medicine Trisakti University 2015-04-01
Series:Universa Medicina
Subjects:
EPP
Online Access:http://www.univmed.org/wp-content/uploads/2015/06/Budi.pdf