Exploratory Investigation on Functional Significance of ETS2 and SIM2 Genes in Down Syndrome

Trisomy of the 21st chromosome leads to an over dosage of several regulatory genes in Down syndrome (DS). Though allelic and genotypic combinations formed between genes are interesting, till date, this particular area has never been explored in DS. In the present investigation four SNPs in two trans...

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Bibliographic Details
Main Authors: Arpita Chatterjee, Samikshan Dutta, Swagata Sinha, Kanchan Mukhopadhyay
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0825