The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts

<p>Abstract</p> <p>Background</p> <p>The COOH terminal peptide of Pro-collagen type I (PICP, also called C3) is chemotactic for endothelial melanoma and breast cancer cells. PICP induces the expression of Metalloproteinases-2 and -9, of Vascular endothelial growth facto...

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Bibliographic Details
Main Authors: Barbieri Ottavia, Astigiano Simonetta, Strangio Antonella, Palmieri Daniela, Visigalli Davide, Casartelli Gianluigi, Zicca Antonio, Manduca Paola
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/59