The ARE-binding protein Tristetraprolin (TTP) is a novel target and mediator of calcineurin tumor suppressing function in the skin.

An increased incidence of skin inflammatory diseases is frequently observed in organtransplanted patients being treated with calcineurin inhibitor-based immunosuppressive agents. The mechanism of increased skin inflammation in this context has however not yet been clarified. Here we report an increa...

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Bibliographic Details
Main Authors: Xunwei Wu, Alice Tommasi di Vignano, Qian Zhou, Piotr J Michel-Dziunycz, Fuxiang Bai, Jun Mi, Jing Qin, Tingjian Zu, Günther F L Hofbauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5953486?pdf=render