Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma

Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma

Abstract Glioma is a unique neoplastic disease that develops exclusively in the central nervous system (CNS) and rarely metastasizes to other tissues. This feature strongly implicates the tumor-host CNS microenvironment in gliomagenesis and tumor progression. We investigated the differences and simi...

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Bibliographic Details
Main Authors: Nina P. Connolly, Amol C. Shetty, Jesse A. Stokum, Ina Hoeschele, Marni B. Siegel, C. Ryan Miller, Anthony J. Kim, Cheng-Ying Ho, Eduardo Davila, J. Marc Simard, Scott E. Devine, John H. Rossmeisl, Eric C. Holland, Jeffrey A. Winkles, Graeme F. Woodworth
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-19451-6

Internet

https://doi.org/10.1038/s41598-018-19451-6

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