Computational detection of alternative exon usage

Computational detection of alternative exon usage

Background: With the advent of the GeneChip Exon Arrays, it is now possible to extract "exon-level" expression estimates, allowing for detection of alternative splicing events, one of the primary mechanisms of transcript diversity. In the context of 1) a complex trait use case and...

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Bibliographic Details
Main Authors: Ted G Laderas, Nicole A R Walter, Michael Mooney, Kristina Vartanian, Priscila Darakjian, Kari Buck, Christina A Harrington, John Belknap, Robert Hitzemann, Shannon K McWeeney
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-05-01
Series:Frontiers in Neuroscience
Subjects:
Alternative Splicing
Software
Microarray
Exon Array
Strain-Specific Alternative Splicing
Transcript Level Modeling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00069/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00069/full

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