Effect of Early Post-Transplantation Tacrolimus Concentration on the Risk of Acute Graft-Versus-Host Disease in Allogenic Stem Cell Transplantation

Effect of Early Post-Transplantation Tacrolimus Concentration on the Risk of Acute Graft-Versus-Host Disease in Allogenic Stem Cell Transplantation

Acute graft versus host disease (aGVHD) remains a leading cause of morbidity and mortality in allogeneic hematopoietic stem cell transplant (allo-HSCT). Tacrolimus (TAC), a calcineurin inhibitor that prevents T-cell activation, is commonly used as a GVHD prophylaxis. However, there is variability in...

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Bibliographic Details
Main Authors: Nidhi Sharma, Qiuhong Zhao, Bin Ni, Patrick Elder, Marcin Puto, Don M. Benson, Ashley Rosko, Maria Chaudhry, Srinivas Devarakonda, Naresh Bumma, Abdullah Khan, Sumithira Vasu, Samantha Jaglowski, Basem M. William, Alice Mims, Hannah Choe, Karilyn Larkin, Jonathan Brammer, Sarah Wall, Nicole Grieselhuber, Ayman Saad, Sam Penza, Yvonne Efebera
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
tacrolimus
graft versus host disease
allogeneic stem cell transplantation
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Online Access:https://www.mdpi.com/2072-6694/13/4/613

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https://www.mdpi.com/2072-6694/13/4/613

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