Crystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870
Multiple subtypes of dopamine receptors within the GPCR superfamily regulate neurological processes through various downstream signaling pathways. A crucial question about the dopamine receptor family is what structural features determine the subtype-selectivity of potential drugs. Here, we report t...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/48822 |