Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

Abstract Background Chronic alcohol consumption is associated with neuroinflammation, neuronal damage, and behavioral alterations including addiction. Alcohol-induced neuroinflammation is characterized by increased expression of proinflammatory cytokines (including TNFα, IL-1β, and CCL2) and microgl...

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Bibliographic Details
Main Authors: Patrick P. Lowe, Caroline Morel, Aditya Ambade, Arvin Iracheta-Vellve, Erica Kwiatkowski, Abhishek Satishchandran, Istvan Furi, Yeonhee Cho, Benedek Gyongyosi, Donna Catalano, Eric Lefebvre, Laurent Fischer, Star Seyedkazemi, Dorothy P. Schafer, Gyongyi Szabo
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Neuroinflammation
Subjects:
Macrophage
Microglia
Alcohol
Neuroinflammation
Cytokines
Online Access:http://link.springer.com/article/10.1186/s12974-020-01972-5

Internet

http://link.springer.com/article/10.1186/s12974-020-01972-5

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