ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis

Background: Gene silencing through CpG island hypermethylation is a major mechanism in cancer development. In the present study, we aimed to identify and validate novel target genes inactivated through promoter hypermethylation in colorectal tumor development. Methods: With the use of microarrays, t...

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Bibliographic Details
Main Authors: Guro E. Lind, Kristine Kleivi, Gunn I. Meling, Manuel R. Teixeira, Espen Thiis-Evensen, Torleiv O. Rognum, Ragnhild A. Lothe
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2006/949506