Myosin 10 Regulates Invasion, Mitosis, and Metabolic Signaling in Glioblastoma

Myosin 10 Regulates Invasion, Mitosis, and Metabolic Signaling in Glioblastoma

Summary: Invasion and proliferation are defining phenotypes of cancer, and in glioblastoma blocking one stimulates the other, implying that effective therapy must inhibit both, ideally through a single target that is also dispensable for normal tissue function. The molecular motor myosin 10 meets th...

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Bibliographic Details
Main Authors: Rajappa S. Kenchappa, Panagiotis Mistriotis, Emily Wisniewski, Santanu Bhattacharya, Tanmay Kulkarni, Rita West, Amanda Luu, Meghan Conlon, Ernest Heimsath, James F. Crish, Hannah S. Picariello, Athanassios Dovas, Natanael Zarco, Montserrat Lara-Velazquez, Alfredo Quiñones-Hinojosa, John A. Hammer, Debrabrata Mukhopadhyay, Richard E. Cheney, Konstantinos Konstantopoulos, Peter Canoll, Steven S. Rosenfeld
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Cell Biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309998

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http://www.sciencedirect.com/science/article/pii/S2589004220309998

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