HIF-1α promoted vasculogenic mimicry formation in lung adenocarcinoma through NRP1 upregulation in the hypoxic tumor microenvironment

HIF-1α promoted vasculogenic mimicry formation in lung adenocarcinoma through NRP1 upregulation in the hypoxic tumor microenvironment

Abstract Neovascularization is a key factor that contributes to tumor metastasis, and vasculogenic mimicry (VM) is an important form of neovascularization found in highly invasive tumors, including lung cancer. Despite the increasing number of studies focusing on VM, the mechanisms underlying VM for...

Full description

Bibliographic Details
Main Authors: Ran Fu, Wenwen Du, Zongli Ding, Yi Wang, Yue Li, Jianjie Zhu, Yuanyuan Zeng, Yulong Zheng, Zeyi Liu, Jian-an Huang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03682-z

Internet

https://doi.org/10.1038/s41419-021-03682-z

Similar Items