Evolutionary consequences of antibiotic use for the resistome, mobilome and microbial pangenome
The widespread use and abuse of antibiotic therapy has evolutionary and ecological consequences, some of which are only just beginning to be examined. One well known consequence is the fixation of mutations and lateral gene transfer events that confer antibiotic resistance. Sequential selection even...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2013-01-01
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Series: | Frontiers in Microbiology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00004/full |