Impact of different oseltamivir regimens on treating influenza A virus infection and resistance emergence: insights from a modelling study.

Several studies have proven oseltamivir to be efficient in reducing influenza viral titer and symptom intensity. However, the usefulness of oseltamivir can be compromised by the emergence and spread of drug-resistant virus. The selective pressure exerted by different oseltamivir therapy regimens hav...

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Bibliographic Details
Main Authors: Laetitia Canini, Jessica M Conway, Alan S Perelson, Fabrice Carrat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24743564/pdf/?tool=EBI