Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism

Accumulation of modified nucleotides is defective to variouscellular processes, especially those involving DNA and RNA.To be viable, organisms possess a number of (deoxy)nucleotidephosphohydrolases, which hydrolyze these nucleotidesremoving them from the active NTP and dNTP pools.Deamination of puri...

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Bibliographic Details
Main Authors: Oluwafemi Davies, Pedro Mendes, Kieran Smallbone, Naglis Malys
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-04-01
Series:BMB Reports
Subjects:
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS00JTVEMTIwNDI2MTkxN18lMjgyNTktMjY0JTI5Qk1CXzExLTE2OS5wZGY=