Pertussis toxin stimulates IL-17 production in response to Bordetella pertussis infection in mice.

In a mouse model of respiratory tract infection by Bordetella pertussis, bacteria multiply in the airways over the first week and are then cleared over the next 3-4 weeks by the host immune response. Pertussis toxin (PT), a virulence factor secreted exclusively by B. pertussis, promotes bacterial gr...

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Bibliographic Details
Main Authors: Charlotte Andreasen, Daniel A Powell, Nicholas H Carbonetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2738961?pdf=render