Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis.

Recently we described a new, evolutionarily conserved cellular stress response characterized by a reversible reorganization of endoplasmic reticulum (ER) membranes that is distinct from canonical ER stress and the unfolded protein response (UPR). Apogossypol, a putative broad spectrum BCL-2 family a...

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Bibliographic Details
Main Authors: Shankar Varadarajan, Kayoko Tanaka, Joshua L Smalley, Edward T W Bampton, Maurizio Pellecchia, David Dinsdale, Gary B Willars, Gerald M Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3574070?pdf=render