Bromofatty aldehyde derived from bromine exposure and myeloperoxidase and eosinophil peroxidase modify GSH and protein

Bromofatty aldehyde derived from bromine exposure and myeloperoxidase and eosinophil peroxidase modify GSH and protein

α-Chlorofatty aldehydes (α-ClFALDs) and α-bromofatty aldehydes (α-BrFALDs) are produced in activated neutrophils and eosinophils. This study investigated the ability of α-BrFALD and α-ClFALD to react with the thiols of GSH and protein cysteinyl residues. Initial studies showed that 2-bromohexadecana...

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Bibliographic Details
Main Authors: Mark A. Duerr, Elisa N.D. Palladino, Celine L. Hartman, James A. Lambert, Jacob D. Franke, Carolyn J. Albert, Sadis Matalon, Rakesh P. Patel, Arne Slungaard, David A. Ford
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Journal of Lipid Research
Subjects:
fatty aldehydes
glutathione
plasmalogen
hypochlorous acid
hypobromous acid
thiols
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339201

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http://www.sciencedirect.com/science/article/pii/S0022227520339201

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