Chronic Microdose Lithium Treatment Prevented Memory Loss and Neurohistopathological Changes in a Transgenic Mouse Model of Alzheimer's Disease.

The use of lithium is well established in bipolar disorders and the benefits are being demonstrated in neurodegenerative disorders. Recently, our group showed that treatment with microdose lithium stabilized the cognitive deficits observed in Alzheimer's disease (AD) patients. In order to verif...

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Main Authors: Marielza Andrade Nunes, Natalia Mendes Schöwe, Karla Cristina Monteiro-Silva, Ticiana Baraldi-Tornisielo, Suzzanna Ingryd Gonçalves Souza, Janaina Balthazar, Marilia Silva Albuquerque, Ariadiny Lima Caetano, Tania Araujo Viel, Hudson Sousa Buck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4659557?pdf=render