S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes

S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes

Abstract Background The secretion of soluble factors enables communication between tumour cells and the surrounding microenvironment and plays an important role in oncogenesis. Pancreatic ductal adenocarcinoma (PDAC) is characterised by a highly reactive microenvironment, harbouring a variety of cel...

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Bibliographic Details
Main Authors: Taoufik Nedjadi, Anthony Evans, Adnan Sheikh, Lawrence Barerra, Suliman Al-Ghamdi, Lucy Oldfield, W. Greenhalf, John P. Neoptolemos, Eithne Costello
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Pancreatic Cancer
Stroma
S100A8
S100A9
Cytokines
Monocytes
Online Access:http://link.springer.com/article/10.1186/s12885-018-5161-4

Internet

http://link.springer.com/article/10.1186/s12885-018-5161-4

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