Suppression of the Insulin Receptors in Adult Schistosoma japonicum Impacts on Parasite Growth and Development: Further Evidence of Vaccine Potential.

To further investigate the importance of insulin signaling in the growth, development, sexual maturation and egg production of adult schistosomes, we have focused attention on the insulin receptors (SjIRs) of Schistosoma japonicum, which we have previously cloned and partially characterised. We now...

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Bibliographic Details
Main Authors: Hong You, Geoffrey N Gobert, Pengfei Cai, Rong Mou, Sujeevi Nawaratna, Guofu Fang, Francois Villinger, Donald P McManus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4427307?pdf=render