Aberrantly Glycosylated IgA1 in IgA Nephropathy: What We Know and What We Don’t Know

IgA nephropathy (IgAN), the most common primary glomerular disease worldwide, is characterized by glomerular deposition of IgA1-containing immune complexes. The IgA1 hinge region (HR) has up to six clustered <i>O</i>-glycans consisting of Ser/Thr-linked <i>N</i>-acetylgalacto...

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Bibliographic Details
Main Authors: Yukako Ohyama, Matthew B. Renfrow, Jan Novak, Kazuo Takahashi
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/16/3467