Oral Delivery of Nucleic Acids with Passive and Active Targeting to the Intestinal Tissue Using Polymer-Based Nanocarriers

Oral Delivery of Nucleic Acids with Passive and Active Targeting to the Intestinal Tissue Using Polymer-Based Nanocarriers

Despite the apparent advantages for long-term treatment and local therapies against intestinal diseases, the oral delivery of nucleic acids has been challenging due to unfavorable physiological conditions for their stability. In this study, a novel nanodelivery system of PEG-PCL nanoparticles with e...

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Bibliographic Details
Main Authors: Sagun Poudel, Prabhat R. Napit, Karen P. Briski, George Mattheolabakis
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
mannosylated PEI
nanoparticles
oral delivery
nucleic acids
targeting
Online Access:https://www.mdpi.com/1999-4923/13/7/1075

Internet

https://www.mdpi.com/1999-4923/13/7/1075

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