Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: Implications for therapeutic targeting of astroglia

Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: Implications for therapeutic targeting of astroglia

The neuropathogenesis of HIV associated neurocognitive disorders (HAND) involves disruption of mitochondrial homeostasis and increased neuroinflammation. However, it is unknown if alterations in mitochondrial biogenesis in the brain underlie the neuropathogenesis of HAND. In this study, neuropatholo...

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Bibliographic Details
Main Authors: Mary K. Swinton, Aliyah Carson, Francesca Telese, Ana B. Sanchez, Benchawanna Soontornniyomkij, Leila Rad, Isabella Batki, Brandi Quintanilla, Josué Pérez-Santiago, Cristian L. Achim, Scott Letendre, Ronald J. Ellis, Igor Grant, Anne N. Murphy, Jerel Adam Fields
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119301561

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http://www.sciencedirect.com/science/article/pii/S0969996119301561

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