The transcriptional activator of the bfp operon in EPEC (PerA) interacts with the RNA polymerase alpha subunit

Abstract Enteropathogenic E. coli virulence genes are under the control of various regulators, one of which is PerA, an AraC/XylS-like regulator. PerA directly promotes its own expression and that of the bfp operon encoding the genes involved in the biogenesis of the bundle-forming pilus (BFP); it a...

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Bibliographic Details
Main Authors: Cristina Lara-Ochoa, Fabiola González-Lara, Luis E. Romero-González, Juan B. Jaramillo-Rodríguez, Sergio I. Vázquez-Arellano, Abraham Medrano-López, Lilia Cedillo-Ramírez, Ygnacio Martínez-Laguna, Jorge A. Girón, Ernesto Pérez-Rueda, José Luis Puente, J. Antonio Ibarra
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87586-0