A Case of CCDC6-RET Fusion Mutation in Adult Acute Lymphoblastic Leukemia (ALL), a Known Activating Mutation Reported in ALL

We report the case of a patient with B-Cell Acute Lymphoblastic Leukemia (ALL) who was found to harbor a gene fusion involving the CCDC6 and RET genes. Although the RET mutations have been identified before in other malignancies, and it is thought to represent a driver mutation in these neoplasms, i...

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Bibliographic Details
Main Authors: Mateo Mejia Saldarriaga, Amir Steinberg, Eric A. Severson, Adam Binder
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
RET
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01303/full