Adding a C-terminal Cysteine (CTC) Can Enhance the Bactericidal Activity of Three Different Antimicrobial Peptides

Adding a C-terminal Cysteine (CTC) Can Enhance the Bactericidal Activity of Three Different Antimicrobial Peptides

The emergence of antibiotic-resistant bacteria has threatened our health worldwide. There is an urgent need for novel antibiotics. Previously, we identified a novel 37-mer antimicrobial peptide (AMP), HBcARD, with broad spectrum antimicrobial activity. Here, we improved the efficacy of HBcARD, by re...

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Bibliographic Details
Main Authors: Heng-Li Chen, Pei-Yi Su, Shu-Chen Kuo, Tsai-Ling Y. Lauderdale, Chiaho Shih
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial peptide
drug resistance
A. baumannii
S. aureus
sepsis
lung infection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01440/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01440/full

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