Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone

Cellular senescence is a process of physiological growth arrest that can be induced by intrinsic or extrinsic stress signals. Some cancer therapies are associated with senescence of cancer cells with a typical cell cycle arrest. Doxorubicin (Dox) induces senescence by a p53-dependent pathway and tel...

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Bibliographic Details
Main Authors: Ali H. El-Far, Noureldien H. E. Darwish, Shaker A. Mousa PhD, MBA, FACC, FACB
Format: Article
Language:English
Published: SAGE Publishing 2020-01-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/1534735419901160