Collagenous Alzheimer amyloid plaque component impacts on the compaction of amyloid-β plaques

Collagenous Alzheimer amyloid plaque component impacts on the compaction of amyloid-β plaques

Abstract Massive deposition of amyloid β peptides (Aβ) as senile plaques (SP) characterizes the brain pathology of Alzheimer’s disease (AD). SPs exhibit a variety of morphologies, although little is known about the SP components that determine their morphology. Collagenous Alzheimer amyloid plaque c...

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Bibliographic Details
Main Authors: Tadafumi Hashimoto, Daisuke Fujii, Yasushi Naka, Mayu Kashiwagi-Hakozaki, Yuko Matsuo, Yusuke Matsuura, Tomoko Wakabayashi, Takeshi Iwatsubo
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer’s disease/amyloid
β peptide/CLAC/senile plaques
Online Access:https://doi.org/10.1186/s40478-020-01075-5

Internet

https://doi.org/10.1186/s40478-020-01075-5

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