Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions
Mutations in the gene encoding LRRK2 (leucine-rich repeat kinase 2) were first identified in 2004 and have since been shown to be the single most common cause of inherited Parkinson's disease. The protein is a large GTP-regulated serine/threonine kinase that additionally contains several protei...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2009-03-01
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Series: | ASN Neuro |
Online Access: | https://doi.org/10.1042/AN20090007 |