Effects of Membrane and Biological Target on the Structural and Allosteric Properties of Recoverin: A Computational Approach

Effects of Membrane and Biological Target on the Structural and Allosteric Properties of Recoverin: A Computational Approach

Recoverin (Rec) is a prototypical calcium sensor protein primarily expressed in the vertebrate retina. The binding of two Ca<sup>2+</sup> ions to the functional EF-hand motifs induces the extrusion of a myristoyl group that increases the affinity of Rec for the membrane and leads to the...

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Bibliographic Details
Main Authors: Alberto Borsatto, Valerio Marino, Gianfranco Abrusci, Gianluca Lattanzi, Daniele Dell’Orco
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
recoverin
myristoyl switch
molecular dynamics
phototransduction
rhodopsin kinase
protein structure networks
Online Access:https://www.mdpi.com/1422-0067/20/20/5009

Internet

https://www.mdpi.com/1422-0067/20/20/5009

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