The Association of Suppressed Hypoxia-Inducible Factor-1 Transactivation of Angiogenesis With Defective Recovery From Cerebral Ischemic Injury in Aged Rats

The Association of Suppressed Hypoxia-Inducible Factor-1 Transactivation of Angiogenesis With Defective Recovery From Cerebral Ischemic Injury in Aged Rats

Elderly patients suffer more brain damage in comparison with young patients from the same ischemic stroke. The present study was undertaken to test the hypothesis that suppressed hypoxia-inducible factor-1 (HIF-1) transcription activity is responsible for defective recovery after ischemic stroke in...

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Bibliographic Details
Main Authors: Yingjia Guo, Junpeng Zhou, Xianglong Li, Ying Xiao, Jingyao Zhang, Yutao Yang, Li Feng, Y. James Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
aging
ischemic stroke
MCAO
hypoxia-inducible factor-1
Cu metabolism MURR domain 3
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.648115/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.648115/full

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