Glyceraldehyde-3-phosphate dehydrogenase from Eimeria acervulina modulates the functions of chicken dendritic cells to boost Th1 type immune response and stimulates autologous CD4+ T cells differentiation in-vitro

Abstract Dendritic cells (DCs) play a pivotal role to amplify antigen-specific immune responses. Antigens that sensitize T cells via antigen-presentation by DCs could enhance the capacity of host immunity to fight infections. In this study, we tested the immunogenic profiles of chicken DCs towards G...

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Bibliographic Details
Main Authors: Shakeel Ahmed Lakho, Muhammad Haseeb, Jianmei Huang, Zhang Yang, Muhammad Waqqas Hasan, Muhammad Tahir Aleem, Muhammad Ali-ul-Husnain Naqvi, Muhammad Ali Memon, XiaoKai Song, RuoFeng Yan, Lixin Xu, XiangRui Li
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Veterinary Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13567-020-00864-z