NPM1 gene mutations in children with Myelodysplastic syndromes

NPM1 gene mutations in children with Myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are rare in children and only a few studies have analyzed their molecular mechanisms. The NPM1 gene encodes for nucleophosmin (NPM) which regulates hematopoiesis. Mutations in exon 12 of the NPM1 cause the nucleophosmin cytoplasmic dislocation and disrupt its func...

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Bibliographic Details
Main Authors: Jekić Biljana, Bunjevački Vera, Dobričić Valerija, Novaković Ivana, Milašin Jelena, Popović Branka, Damnjanović Tatjana, Maksimović Nela, Perović V., Luković Ljiljana
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2011-01-01
Series:Archives of Biological Sciences
Subjects:
Myelodysplastic syndromes
nucleophosmin
NPM1 mutation
children
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2011/0354-46641103649J.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2011/0354-46641103649J.pdf

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